IGF-1 LR3

IGF-1 LR3 (Long R3 Insulin-Like Growth Factor-1) is an 83-amino acid synthetic analog of IGF-1 with an arginine substitution at position 3 and a 13-amino acid N-terminal extension. These modifications significantly reduce binding to IGF binding proteins (IGFBPs), resulting in enhanced bioavailability and a substantially longer half-life compared to native IGF-1.

Molecular Profile:

• Molecular Weight: 9,111 g/mol
• Length: 83 amino acids (vs. 70 for native IGF-1)
• Modification: Arg³ substitution + 13-AA N-terminal extension
• CAS Number: 946870-92-4

Research Applications:

• Cell proliferation and hyperplasia studies
• Muscle satellite cell activation research
• IGFBP-independent IGF-1 receptor signaling
• Glucose uptake and insulin sensitization pathways
• Protein synthesis and nitrogen balance models
• Anti-apoptotic mechanism investigation

Quality Standards:

• Purity: ≥99% verified by HPLC
• Third-party tested with COA included

FOR RESEARCH USE ONLY. Not for human consumption.